While still studying voice and piano, in 1992 Šárka Knížetová was engaged at the J. K. Tyl Theatre in Plzeň, where she was a member of the chorus and a piano accompanist. In 1995, she joined the State Opera Prague Chorus, yet since 1998 she has fully devoted to coaching. Following an audition in 2002, she was engaged for a year as a repetiteur at the Wiener Staatsoper. Since 2003, she has served as a repetiteur at the State Opera in Prague, where she has also been an external member of the chorus, and in 2013 was appointed chief repetiteur. Šárka Knížetová has also occasionally performed at concerts. She speaks Czech, German, Italian and French, and, besides spending time with her family, she enjoys astrology and travel.